Your strong partner in the corona research

BINDER constant climate chambers: Corona vaccines are tested for shelf life

Never before have vaccines been developed in such a short time as it is currently the case during the Corona pandemic. Some, such as those from Biontech and Pfizer, are even already on the market and are being vaccinated at lightning speed. But what about the shelf life of the new vaccines? And that is exactly what the major pharmaceutical manufacturers are currently testing in constant climate chambers from BINDER. Normally, vaccine development takes between ten and twenty years. This time is not available during the Corona crisis. The number of infected people and also the number of deaths is too high. The call for a rapid vaccination campaign is growing louder and louder. The pharmaceutical companies can hardly keep up with production, but they also concentrate on analyzing the stability of the vaccines. After all, the Corona vaccines will now be available annually, always adapted to certain viral changes, of course. And this is how it works in practice: the stability tests take place, for example, in a KBF or in a KBF LQC, i.e. in a constant climate chamber with ICH-compliant lighting and light dose control.


Smart, safe, economical and reliable: that's BINDER.


And why do major pharmaceutical companies choose BINDER? One reason is that the chambers from Tuttlingen can be used for testing according to ICH guidelines. In addition, the BINDER chambers have a large interior, so that 30 percent more samples can be tested. On top comes the temperature accuracy of the constant climate chambers. BINDER offers climate conditions that are four times more precise than the competition, as well as faster recovery times. Last but not least, the constant climate chambers are particularly impressive because of their lifetime.


But why are the Corona vaccines actually stressed? The pharmaceutical companies have made it their goal to be able to confirm the efficacy of the vaccines to the public even after a longer period of time or after storage periods at different temperatures. It is too early at this point to say how individual vaccines will perform under changing conditions. But one thing is certain: BINDER is your reliable partner in the Corona pandemic.

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Professor Thiel focuses on coronaviruses

Swiss virologDr-Thiel-400x250pxist Professor Volker Thiel is a man in high demand – and his name is now known around the world following his success in creating the first synthetic coronavirus clone at the end of March 2020.
During that month, Professor Thiel and his team at Mittelhäusern high-security laboratory in Switzerland worked with genuine coronavirus samples virtually non-stop. Their efforts were assisted by BINDER freezers with the ability to establish conditions of minus 80°C – the perfect temperature for storing the samples. Supplied by Tuttlingen-based global market leader BINDER, the equipment has been a stalwart of Thiel’s work to date.
Thiel has been focusing on coronaviruses for a number of years now – but his work had been viewed in some circles as an unusual choice due to the lesser significance that these viruses were thought to have. The situations surrounding SARS and MERS, also types of coronavirus, led the general public to begin shifting their opinions, however.
Viruses of the coronavirus kind are extremely small – to quote Thiel, “A milliliter of sea water contains a million viruses.” He adds that viruses have their own unique structure and require the support of the cells they infect in order to multiply. As for the name “coronavirus”, he explains that the term “corona” refers to a crown shape, reflecting the appearance of the virus when it is placed under the microscope.
Thiel and his research group are currently working with pharmaceutical companies with the aim of bringing a vaccine to market as quickly as possible. He explains what is involved in this fundamental research: “We create mucous membranes, infect them with the virus, and try to determine the temperatures at which it multiplies.”
While Thiel and his team are making good progress, they do not envisage a vaccine becoming available to the population at large before 2021. Thiel also believes that vaccination is the best way forward in the current crisis: “Without it, the situation as it stands just isn’t going to change.” These are views that are shared by virologist and frequent collaborator Christian Drosten from Charité university hospital in Berlin.


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BINDER fights COVID-19

BINDER Drying chambers, Freezers and CO2-incubators will support you in this pandemic!

Drying ovens: Prevent a shortage of face masks

Expose the face masks to dry heat of 65 to 70 degrees Celsius for 30 minutes. This will deactivate the corona virus and decontaminate the masks.




Freezer: Cool down to - 80 °C

or example, coronavirus samples are stored in the freezers, which cool down to - 80 °C. In this way, they can be retrieved at any time and can provide further information on the new lung disease. Freezers from BINDER thus enable detailed and long-term virus research with dangerous pathogens.


CO2 incubators: Optimum cell growth

Those who deal with the coronavirus scientifically will probably also need a CO2 - incubator for their research. The most important issue here is safety and the fact that after working on human cells, an anti-contamination concept such as that used by BINDER is available.

 

Constant climate chambers: stability tests with Corona vaccines

Major pharmaceutical companies test the shelf life of corona vaccines in BINDER constant climate chambers around the world. The homogeneous temperature distribution inside the chamber for this type of testing is highly valued among experts.

Our premium equipment for coronavirus research

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ULT Freezers

  • Lowest energy consumption in its class
  • Environmentally-friendly refrigerants R-290 and R-170
  • Range of temperature controller: -90 °C to -40 °C
  • Efficient thermal insulation with vacuum insulation panels
  • Rust-proof interior made completely of stainless steel


CO2 Incubators

  • Maximum usable space with minimal footprint and excellent ease of use
  • Minimum risk of contamination thanks to uncompromising hot-air sterilization
  • Fanless, easy-to-clean hygienic interior without fixtures
  • Stable pH values thanks to drift-free CO₂ IR sensor technology
  • Low evaporation of the medium due to high levels of humidity and quick recovery time


 Ovens

  • Temperature range up to 300°C
  • Excellent temporal and spatial temperature accuracy
  • Up to 30% lower energy consumption compared to conventional units on the market
  • Constant climate chambers


 Constant climate chambers

  • Temperature range: 0 °C to +70 °C
  • Humidity range from 10 % r.H. to 80 % r.H.
  • Humidity control with capacitive humidity sensor and steam humidification
  • Intuitive touch screen controller with time segment and real time programming

Do not hesitate and ask us how our chambers can help you in your important work. We will be pleased to advise you which chambers meet your requirements.